Nintendo announced at its E3 press briefing several "hardcore" franchises and games coming to the Wii U console. Among the named titles in the teaser video were Darksiders 2, Batman: Arkham City, Ghost Recon Online, Aliens: Colonial Marines, Metro: Last Light, Dirt, Tekken, and Ninja Gaiden 3. Ubisoft's Yves Guillemot also mentioned Assassin's Creed, but didn't specify a particular game.
Nintendo's press conference is still ongoing. Shacknews will update as more information becomes available.