The Last of Us developed by Uncharted team

The Spike TV Video Game Awards took only ten minutes to get to its first big reveal. The Last of Us, the long-teased mysterious PS3 exclusive, is reminiscent of the Dead Island debut trailer, showing a family struggling against monsters in a post-apocalyptic setting. The game is being developed by Naughty Dog, the team best known for their work on the Uncharted franchise.

A girl that "sounds like Haley Joel," according to Garnett and "looks like Ellen Paige" according to Xav appears to be the game's main protagonist. See for yourself:

The PlayStation.Blog has been updated with the game's premise:

The Last of Us is a genre-defining experience that blends survival and action elements to tell a character driven tale about a modern plague decimating mankind. Nature encroaches upon civilization, forcing remaining survivors to kill for food, weapons and whatever they can find. Joel, a ruthless survivor, and Ellie, a brave young teenage girl who is wise beyond her years, must work together to survive their journey across what remains of the United States.