Peter Molyneux talked about role-playing games as one of his favorite types of games, and he had some very concrete ideas about what he might like to see in an RPG. The central theme of his idea is a living world that reacts to players' actions and changes over time--an idea that extends what Molyneux has already done in Black & White in terms of creature development and the effect of a player's alignment in the world.

While there you might want to check out some of the first details on Black&White2