The American Football game will feature 11-on-11 and 5v5 matches plus a Season Mode, with three types of play calling--GameFlow, Arcade and Classic--offering different levels of complexity and control. You can also draw your own plays on the touchscreen.
Madden NFL Football will launch when Nintendo's glasses-free-3D-supporting handheld does, which is due to be some time in March 2011.
Cool. I just hope Ocarina of Time is a launch title.