Over at PC.IGN you can find a preview of Deus Ex 2, currently in development at ION Austin. The preview has several quotes by Warren Spector, about such things as the modified Unreal Warfare engine, and the gameplay, which should be partly similar to Deus Ex 1 but Warren mentions ION will be encouraging non-combat options (they hope to be able to create a way of getting through the game where you never draw a weapon)

As good as the gameplay was, Warren is committed to pushing it into new directions. The team's goal is to craft a "much more robust simulation on all levels." This means creating a wider range of natural reactions on the part of the NPCs to the player's actions. The ability of the player to feel like he or she is in control of his or her own destiny is paramount. There were far too many pre-scripted events in Deus Ex -- moments where the game took over and forced the player into or out of particular situations. But although the goal is to make "the game world work the way the real world works" the team ardently follows the rule of all good game designers: "Anytime reality gets in the way of fun, fun wins."