Garnett in not alone his ethusiasm for the storyline in Resident Evil 6. Never before have so many classic characters appeared in a single Resident Evil game. This is "The Avengers" of Resident Evil!
Not excited? That's cool but don't be a hypocrite. We all have our favorite franchises. For example, I've never played Mass Effect yet I don't mind all the gushing about details that make no sense to me. Also, I think that those unfamiliar with the Resident Evil backstory will still have fun experiencing the characters and concepts in 6.