Again it is apparent whoever made this decision has not played the game, and doesn't care about the fans who made the series a hit. When the community comes out and asks for an actor to play the role, and you go in a different direction you might as well have Uwe Boll direct it.
De Niro? Joe Pesci? Give me a break. Throw those guys out, cast Danial Craig as the villain with Nathan Fillion as the hero, and the girl who did the voice work for uncharted as the girl. For crying out loud I can guarantee a $30 million take with just that cast and no plot for opening weekend.